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Vitamin and Supplement Therapy
Some Info thanks to Association for Science in Autism Treatment

Beneficial results from different vitamin therapies have been documented for symptoms and behaviors normally associated with
Autism.  Dr. Bernard Rimland, a leader in the modern field of
Autism treatment research, has pointed out as far back as the
1960's as to the beneficial results obtained with Vitamin B6 and Magnesium supplements.

Since then, other physicians and parents have come forward with evidence, both medical research and anecdotal, as to the
different affects of different vitamin therapies with children having Autism.

To truly develop a vitamin therapy program that fits YOUR child, you must do so with the concerted efforts and supervision of a
certified medical physician

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Description: Administration of a vitamin, mineral, or nutritional supplement in the form of a pill, powder, liquid, cream, bath, or
injection.

Examples: Vitamin A; Vitamin B6; Vitamin B12; Vitamin C; Vitamin D; Magnesium; Dimethylglycine (DMG); Calcium; Omega 3
Fatty Acids

Research Summary: Three small but well-designed indicated that B6 with magnesium is ineffective in changing behavior
(Findling et al., 1997; Kuriyama et al., 2002; Tolber, Haigler, Waits, & Dennis, 1993), but further study may be warranted (Nye &
Brice, 2005).

No well-designed studies have evaluated other vitamin and supplement therapies for individuals with autism spectrum disorders.

Recommendations: Researchers may wish to conduct large studies with strong scientific designs to obtain more conclusive
evidence on whether B6 with magnesium is effective or not. Other vitamin therapies also may warrant further study. Professionals
should present vitamin therapy as unsupported by research and encourage families who are considering this intervention to
evaluate its effects and side-effects carefully.


Selected scientific studies:

Findling, R. L., Maxwell, K., Scotese-Wojtila, L., Huang, J., Yamashita, T., & Wiznitzer, M. (1997). High-dose pyridoxine and
magnesium administration in children with autistic disorder: An absence of salutary effects in a double-blind, placebo-controlled
study. Journal of Autism and Developmental Disorders, 27, 467-478.
Kuriyama, S., Kamiyama, M., Watanabe, M., Tamahashi, S., Muraguchi, I., Watanabe, T., et al. (2002). Pyridoxine treatment in a
subgroup of children with pervasive developmental disorders. Developmental Medicine & Child Neurology, 44, 284-246.
Tolbert, L., Haigler, T., Waits, M. M., & Dennis, T. (1993). Brief report: Lack of response in an autistic population to a low dose
clinical trial of pyridoxine plus magnesium. Journal of Autism and Developmental Disabilities, 23, 193-199.
Systematic reviews of scientific studies:

Nye, C., & Brice, A. (2005). Combined vitamin B6-magnesium treatment in autism spectrum disorder. The Cochrane Database of
Systematic Reviews, 4.
It is not the intention of Arizona Autism Support (AAS) to provide specific
medical advice, but rather to provide users with information to better
understand their health and their diagnosed disorders. Specific medical
advice will not be provided, and AAS urges you to consult with a qualified
physician for diagnosis and for answers to your personal questions.